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Animal-Free Recombinant Human IL-10
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Animal-Free Recombinant Human IL-10

品牌：PEPROTECH
货号：AF-200-10
名称：Animal-Free Recombinant Human IL-10
规格：2µg  10µg  50µg  100µg  250µg  500µg  1mg

IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes.  IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNF-α.  Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions.  Human IL-10 is active on murine cells, but murine IL-10 is inactive on human cells.  Recombinant Human IL-10 is an 18.6 kDa protein of 161 amino acid residues.

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商品描述

品牌：PEPROTECH
货号：AF-200-10
名称：Animal-Free Recombinant Human IL-10
规格：2µg  10µg  50µg  100µg  250µg  500µg  1mg

IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes.  IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNF-α.  Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions.  Human IL-10 is active on murine cells, but murine IL-10 is inactive on human cells.  Recombinant Human IL-10 is an 18.6 kDa protein of 161 amino acid residues.

Manufactured using all Animal-Free reagents.


Source:E.coli


Synonyms:B-TCGF, CSIF, TGIF


AA Sequence:MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N


Purity:≥ 98% by SDS-PAGE gel and HPLC analyses.


Biological Activity:Determined by the dose-dependent co-stimulation (with human IL-4) of MC/9 cells.  The expected ED50 is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.

This product has been tested against the WHO standard. International Unit information can be found here.


Calculated Molecular Weight:18.6 kDa


Accession Number:P22301


Gene ID:3586


crossreactivity:

Human, Human + Virus