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Human Activin A Recombinant Protein
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Human Activin A Recombinant Protein

品牌：Gibco
货号：PHC9564
名称：Human Activin A Recombinant Protein
规格：10ug  100ug  1mg
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute lyophilized recombinant human Activin A in sterile PBS containing 0.1% human serum albumin. Further dilutions should be made in low endotoxin medium or a buffered solution containing a carrier protein such as heat inactivated FCS or tissue culture grade BSA.

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商品描述

品牌：Gibco
货号：PHC9564
名称：Human Activin A Recombinant Protein
规格：10ug  100ug  1mg
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute lyophilized recombinant human Activin A in sterile PBS containing 0.1% human serum albumin. Further dilutions should be made in low endotoxin medium or a buffered solution containing a carrier protein such as heat inactivated FCS or tissue culture grade BSA.

应用建议稀释比已发表文章

免疫印迹 (WB)

Assay-dependent-

免疫组化 (IHC)

Assay-dependent-

酶联免疫吸附实验 (ELISA)

Assay-dependent-

功能检测 (FN)

Assay-dependent查看5篇已发表文章

对照试剂 (Ctrl)

Assay-dependent-

产品规格

种属

Mouse, Human

已发表种属

Human, Mouse

表达系统

HEK293 cells

分子量

25 kDa

分类

Recombinant

类型

Protein

纯度

>95% by SDS-PAGE

内毒素浓度

<1 EU/mL

活性

ED50 = 0.5 - 5 ng/mL; determined by the dose-dependent proliferation of MPC-11 cells.

偶联物

Unconjugated

形式

Lyophilized

纯化类型

sequential chromatography

保存液

PBS

内含物

no preservative

保存条件

-20°C

产品详细信息

Carrier-Free

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute lyophilized recombinant human Activin A in sterile PBS containing 0.1% human serum albumin. Further dilutions should be made in low endotoxin medium or a buffered solution containing a carrier protein such as heat inactivated FCS or tissue culture grade BSA.

Storage: Store this lyophilized preparation at ≤ -20°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤ -20°C. Avoid repeated freeze/thaw cycles.

靶标信息

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Activin A mutations are associated with fibrodysplasia ossificans progressive.